Instytutum Claims Biological Skin Age Reversal in 84-Day Study

The open-label study, conducted by an independent European laboratory, monitored 21 women between the ages of 35 and 60. Over the course of 84 days, researchers tracked changes in skin firmness, hydration, and texture, alongside the biological age metric, which dropped from an average of 49.7 years to 46.6 years. Participants reported universal improvements in radiance and smoothness by the conclusion of the trial.

Dr. Natalia Bobok, the brand’s founder and a biotech scientist, positions these results as a shift toward extending the "skinspan" rather than merely masking superficial signs of wear. While the study provides a quantitative look at wrinkle depth and elasticity, the brand notes that these calculations rely on periocular measurements—specifically crow’s feet depth—rather than a systemic medical evaluation of biological aging. The results highlight the company's focus on high-concentration active ingredients and proprietary delivery systems intended to mimic professional-grade dermatological performance at home.