WPI Expands NanoFil Syringe Line for Ultra-Low-Volume Research

The new 5µL syringe is engineered specifically for ultra-low-volume injections where reagent conservation and tissue preservation are vital. Its compact design facilitates independent, handheld operation, allowing for finer tactile feedback than previous models. According to Product Manager Brittany Crafton, the lack of dedicated, handheld-capable systems has long hampered progress in ophthalmology; this addition seeks to bridge that gap by offering a solution previously unavailable in the market.

These syringes utilize a gas-tight, zero-dead-volume design that minimizes sample loss by allowing the needle to insert directly into the glass barrel. By eliminating the need for continuous Teflon pistons, the system ensures a vacuum-seal that maintains high reproducibility. Researchers can pair these with 33-36G needles—the smallest gauges commercially available—featuring tri-bevel tips to reduce mechanical trauma during insertion. The full NanoFil lineup, now including 5, 10, 25, 50, and 100µL configurations, is intended to support complex workflows such as CRISPR-based therapeutics, optogenetics, and stereotaxic brain injections.